Meet married mum of two and successful GP Holly Graham as she relocates her family to The Practice at Larkford, hoping to find a peaceful life despite her two-year-old twins and a troubled marriage. Her colleagues have their own issues to contend with. Gorgeous Dr Dan Carter is struggling to focus on work, and having his ambitious ex-girlfriend Dr Julia Channing working alongside him isn't helping. Thankfully, the delectable Dr Taffy Jones is on hand to distract Holly from the escalating situation at home. Feisty octogenarian and resident celebrity, Elsie Townsend, is Holly's favourite patient. Elsie's inspirational Life Lessons come at the perfect moment, as The Practice comes under threat of imminent closure.